diff --git a/gnu/packages/bioinformatics.scm b/gnu/packages/bioinformatics.scm
index d59c1e2b1a..09886afc7a 100644
--- a/gnu/packages/bioinformatics.scm
+++ b/gnu/packages/bioinformatics.scm
@@ -17049,6 +17049,7 @@ (define-public flair
               (for-each
                (lambda (script)
                  (wrap-program script
+                   `("R_HOME" ":" = (,(string-append #$r-minimal "/lib/R")))
                    `("R_LIBS_SITE" ":" = (,(getenv "R_LIBS_SITE")))))
                (find-files (string-append #$output "/bin"))))))))
     (propagated-inputs