diff --git a/gnu/packages/mail.scm b/gnu/packages/mail.scm
index ed095dd9d4..149315806d 100644
--- a/gnu/packages/mail.scm
+++ b/gnu/packages/mail.scm
@@ -323,7 +323,6 @@ (define-public neomutt
              "--without-ssl"
              "--with-sasl"
 
-             "--with-regex"
              "--enable-smime"
              "--enable-notmuch"
              "--with-idn"
@@ -333,8 +332,6 @@ (define-public neomutt
              ;; in the chroot. The workaround is this.
              "--with-mailpath=/var/mail"
 
-             "--with-external-dotlock"
-
              (string-append "--with-curses="
                             (assoc-ref %build-inputs "ncurses")))
        #:phases