diff --git a/gnu/packages/bioconductor.scm b/gnu/packages/bioconductor.scm
index 6996d9037d..0287df0423 100644
--- a/gnu/packages/bioconductor.scm
+++ b/gnu/packages/bioconductor.scm
@@ -6036,13 +6036,13 @@ (define r-rcppnumerical
 (define-public r-apeglm
   (package
    (name "r-apeglm")
-   (version "1.16.0")
+   (version "1.18.0")
    (source (origin
             (method url-fetch)
             (uri (bioconductor-uri "apeglm" version))
             (sha256
              (base32
-              "11w4vyc1sllmm5lh42krhidazid78n4s3lhikpy9kk2l57jmifbr"))))
+              "1ppwk4g66x46hpqsfsvhl12398d1srqr47nmp0y2gz212kff0rby"))))
    (properties `((upstream-name . "apeglm")))
    (build-system r-build-system)
    (propagated-inputs